Ibon Martínez-Arranz

Currently

Ibon Martínez-Arranz got his B.Sc. in Mathematics at the University of the Basque Country (EHU/UPV) and M.Sc. in Mathematical Modelling, in Mathematical Research and in Statistical and Computing Sciences. He joined the Basque Country Health Service in 2004 as a data analyst, being involved also in the epidemiological report of renal patients (The Department of Health of the Basque Country Government and Osakidetza). Since his incorporation at OWL in 2010, Ibon is responsible of the Data Mining and Predictive Modeling Department of the Company.

Employment

2017 OWL (One Way Liver, S.L.) Big Data Analytics Manager.
Data Processing and Analysis, Statistical Studies and Operational Research. Statistical data processing and analysis. Collaboration in the preparation of technical reports. Elaboration of the statistical methodology used and justification.

2010-2017 OWL (One Way Liver, S.L.) Data Processing and Analysis.
Data Processing and Analysis, Statistical Studies and Operational Research. Statistical data processing and analysis. Collaboration in the preparation of technical reports. Elaboration of the statistical methodology used and justification.

2004-2010 COHS Consultores en Ciencias Humanas, S.L. Data Processing and Analysis.
Data Processing and Analysis, Statistical Studies and Operational Research. Statistical data processing and analysis. Collaboration in the preparation of technical reports. Elaboration of the statistical methodology used and justification.

Structured Programming

Python, FORTRAN, C/C++, Visual Basic

Scientific Programming & Statistics

R, GNUplot, Julia, SPSS, SAS, Matlab, Mathematica

R Utilities

RStudio, RKward, Tinn-R, Sweave, knitr, Rmarkdown, Tidyverse

Python Utilities

ANACONDA, Jupyter

Data Bases & Big Data Analysis

MySQL, spark, H2O

Linear Programming

CPLEX, COIN-OR, GUSEK

Design

LaTeX, Gimp, Inkscape

Office IT

Microsoft Office (Word, PowerPoint, Excel, Access), OpenOffice

OwlStatApp

Metabolomics research has evolved considerably, particularly during the last decade. Over the course of this evolution, the interest in this omic discipline is now more evident than ever. However, the future of metabolomics will depend on its capability to find biomarkers. For that reason, data mining constitutes a challenging task in metabolomics workflow, being a time-consuming issue which usually requires detailed knowledge of bioinformatics, statistics and specialized software. We have developed OWL Stat App, an easy-to-use web application for metabolomics data analysis. It combines powerful univariate and multivariate data analysis with pathway mapping tools and visualization capacities to facilitate interpretation of the results.
| OwlStatApp |

AgingAnalysis

Metabolomics research has evolved considerably, particularly during the last decade. Over the course of this evolution, the interest in this omic discipline is now more evident than ever. However, the future of metabolomics will depend on its capability to find biomarkers. For that reason, data mining constitutes a challenging task in metabolomics workflow. This work has been designed in support of the research article entitled Enhancing metabolomics research through data mining, which proposed a methodological data handling guideline. An aging research in healthy population was used as a guiding thread to illustrate this process. Here we provide a further interpretation of the obtained statistical results. We also focused on the importance of graphical visualization tools as a clue to understand the most common univariate and multivariate data analyses applied in metabolomics.
| AgingAnalysis |

2017

2017 Role of aramchol in steatohepatitis and fibrosis in mice, Marta Iruarrizaga-Lejarreta, Marta Varela-Rey, David Fernández-Ramos, Ibon Martínez-Arranz, Teresa C Delgado, Jorge Simon, Virginia Gutiérrez-de Juan, Laura delaCruz-Villar, Mikel Azkargorta, José L. Lavin, Rebeca Mayo, Sebastiaan M. Van Liempd, Igor Aurrekoetxea, Xabier Buqué, Donatella Delle Cave, Arantza Peña, Juan Rodríguez-Cuesta, Ana M. Aransay, Felix Elortza, Juan M. Falcón-Pérez, Patricia Aspichueta, Liat Hayardeny, Mazen Noureddin, Arun J. Sanyal, Cristina Alonso, Juan Anguita, María Luz Martínez-Chantar, Shelly C. Lu, and José M. Mato,
Hepatology Communications, Volume 1, number 9, November 2017, Pages 911–927
| doi | abstract | html | pubmed | pdf |

2017 Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma, Ander Arbelaiz, Mikel Azkargorta, Marcin Krawczyk, Álvaro Santos-Laso, Ainhoa Lapitz, Maria J. Perugorria, Oihane Erice, Esperanza Gonzalez, Raúl Jimenez-Agüero, Adelaida Lacasta, César Ibarra, Alberto Sánchez-Campos, Juan P. Jimeno, Frank Lammert, Piotr Milkiewicz, Marco Marzioni, Rocio I.R. Macias, José J.G.Marín, Tushar Patel, Gregory J. Gores, Ibon Martinez, Félix Elortza, Juan M. Falcón-Pérez, Luis Bujanda, and Jesus M. Banales,
Hepatology, Volume 66, issue 4, October 2017, Pages 1125–1143
| doi | pubmed |

2017 A Metabolomics Signature Linked To Liver Fibrosis In The Serum Of Transplanted Hepatitis C Patients, Ainara Cano, Zoe Mariño, Oscar Millet, Ibon Martínez-Arranz, Miquel Navasa, Juan Manuel Falcón-Pérez, Miriam Pérez-Cormenzana, Joan Caballería, Nieves Embade, Xavier Forns, Jaume Bosch, Azucena Castro & José María Mato,
Scientific Reports 7, article number: 10497.
| doi | pubmed | pdf |

2017 Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis, Alonso C, Fernández-Ramos D, Varela-Rey M, Martínez-Arranz I, Navasa N, Van Liempd SM, Lavin JL, Mayo R, Ilisso CP, de Juan VG, Iruarrizaga-Lejarreta M, delaCruz-Villar L, Mincholé I, Robinson A, Crespo J, Martín-Duce A, Romero-Gomez M, Sann H, Platon J, Van Eyk J, Aspichueta P, Noureddin M, Falcón-Pérez JM, Anguita J, Aransay AM, Martínez-Chantar ML, Lu SC, Mato JM.,
Gastroenterology, Volume 152, issue 6, May 2017, Pages 1449–1461.e7
| doi | pubmed | pdf |

2016

2016 Metabolically active extracellular vesicles released from hepatocytes under drug-induced liver-damaging conditions modify serum metabolome and might affect different pathophysiological processes, Felix Royo, Laura Palomo, Justyna Mleczko, Esperanza Gonzalez, Cristina Alonso, Ibon Martínez-Arranz, Miriam Pérez-Cormenzana, Azucena Castro, Juan M. Falcon-Perez,
European Journal of Pharmaceutical Sciences, Volume 98, February 2017, Pages 51–57.
| doi | pubmed |

2015

2015 Enhancing metabolomics research through data mining, Martínez-Arranz, I., Mayo, R., Pérez-Cormenzana, M., Mincholé, I., Salazar, L., Alonso, C., José M Mato,
Journal of Proteomics, Volume 127 (Part B), September 2015, Pages 275–288.
| doi | pubmed |

2015 Data in support of enhancing metabolomics research through data mining, Martínez-Arranz, I., Mayo, R., Pérez-Cormenzana, M., Mincholé, I., Salazar, L., Alonso, C., José M Mato,
Data in Brief, Volume 3, June 2015, Pages 155–164.
| doi | pubmed | pdf | web application |

2013

2013 Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis, Maite Martínez-Uña, Marta Varela-Rey, Ainara Cano, Larraitz Fernández-Ares, Naiara Beraza, Igor Aurrekoetxea, Ibon Martínez-Arranz, Juan L García-Rodríguez, Xabier Buqué, Daniela Mestre, Zigmund Luka, Conrad Wagner, Cristina Alonso, Richard H Finnell, Shelly C Lu, M Luz Martínez-Chantar, Patricia Aspichueta, José M Mato,
Hepatology, Octubre de 2013. HEPATOLOGY, Vol. 58, No. 4, 2013
| doi | pubmed | pdf |

2013 Solute carrier family 2 member 1 (SLC2A1) is involved in the development of nonalcoholic fatty liver disease, Vazquez-Chantada, M., Gonzalez-Lahera, A., Martinez-Arranz, I., Garcia-Monzon, C., Maria Regueiro, M., Garcia-Rodriguez, J.L., Karin Anna Schlangen, Mendibil, I., Rodriguez-Ezpeleta, N., Lozano, J.L., Karina Banasik, Johanne M Justesen, Torben Joergensen, Daniel R Witte, Torsten Lauritzen, Torben Hansen, Oluf Pedersen, Nicolas Veyrie, Karine Clement, Joan Tordjman, Albert Tran, Yannik Le Marchand-Brustel, Xabier Buque, Aspichueta, P., Echevarria-Uraga, J.J., Martin-Duce, A., Caballería, J., Philippe Gual, Castro, A., Mato, J.M., Martinez-Chantar, M.L., Aransay, A.M.,
Hepatology, Febrero de 2013. HEPATOLOGY, Vol. 57, No. 2, 2013.
| doi | pubmed |

2012

2012 Metabolic profile associated with alcoholic hepatitis and the response to treatment. Preliminary results, Javier Michelena, Cristina Alonso, José Altamirano, Ibon Martínez-Arranz, Ramón Bataller, MariaLuz Martínez-Chantar, Azucena Castro, Jose M. Mato, Juan Caballería,
Journal of Hepatology, Volume 56, Supplement 2, Pages S535–S536.
| doi |

2012 Obesity dependent metabolic signatures associated with nonalcoholic fatty liver disease progression, Barr, J., Caballería, J., Martínez-Arranz, I., Domínguez Díez, A., Alonso, C., Muntané, J., Pérez Cormenzana, M., García Monzón, C., Mayo, R., Martín Duce, A., Romero Gómez, M., Lo Iacono, O., Tordjman, J., Andrade, R.J., Pérez Carreras, M., le Marchand Brustel, Y., Tran, A., Fernández Escalante, C., Arévalo, E., García Unzueta, M., Clement, K., Crespo, J., Gual, P.,Gómez Fleitas, M., Martínez Chantar, M.L., Castro, A., S.C. Lu, Vázquez Chantada, M., Mato, J.M.,
Journal of Proteome Research, Febrero de 2012. J. Proteome Res. 2012, 11, 2521–2532.
| doi | pubmed |

2011

2011 Unidad de Información sobre Pacientes Renales de la CAPV, 2009, Servicio Central de Publicaciones del Gobierno Vasco, Depósito Legal:, Mayo de 2011.

2009

2009 Unidad de Información sobre Pacientes Renales de la CAPV, 2008, Servicio Central de Publicaciones del Gobierno Vasco, Depósito Legal: BI-2458-09, Octubre de 2009.

2009 Unidad de Información sobre Pacientes Renales de la CAPV, 2007, Servicio Central de Publicaciones del Gobierno Vasco, Depósito Legal: BI-798-09, Abril de 2009.

2008

2008 CERVANTES, Batería Magallanes de Evaluación de la Inteligencia, COHS, Consultores en Ciencias Humanas, ISBN: 978-84-95180-17-9, Octubre de 2008.
| ISBN |

2008 SÓCRATES, Protocolo Magallanes de Evaluación de Variables Moduladoras del Éxito Escolar, COHS, Consultores en Ciencias Humanas, ISBN: 978-84-95180-36-0, Diciembre de 2008.
| ISBN |

2007

2007 Unidad de Información sobre Pacientes Renales de la CAPV, 2006, Servicio Central de Publicaciones del Gobierno Vasco, Depósito Legal: BI-1067-08, Octubre de 2007.

2007 Unidad de Información sobre Pacientes Renales de la CAPV, 2005, Servicio Central de Publicaciones del Gobierno Vasco, Depósito Legal: BI-2871-07, Octubre de 2007.
| Web |

2006

2006 Unidad de Información sobre Pacientes Renales de la CAPV, 2004, Servicio Central de Publicaciones del Gobierno Vasco, Depósito Legal: BI-2020-06, Octubre de 2006.

2006 EMA-DDA, Escalas Magallanes de Detección de Problemas en el Desarrollo, COHS, Consultores en Ciencias Humanas, ISBN: 978-84-95180-26-1, Octubre de 2006.
| ISBN |

2006 ESMIDAS, Escalas Magallanes de Identificación de Déficit de Atención en Niños, Adolescentes y Adultos, COHS, Consultores en Ciencias Humanas, ISBN: 978-84-95180-32-2, Octubre de 2006.
| ISBN |

2005

2005 Escala Magallanes de Inteligencia para Niños: EMIN-6, COHS, Consultores en Ciencias Humanas, ISBN: 978-84-95180-16-2, Agosto de 2005.
| ISBN |

2005 Unidad de Información sobre Pacientes Renales de la CAPV, 2003, Servicio Central de Publicaciones del Gobierno Vasco, Depósito Legal: BI-1240-05, Octubre de 2005.

2005 Ley de Benford o Ley del Primer Dígito Significativo, Martínez Arranz, I., de la Torre Sebastián, L., SIGMA: Revista de Matemáticas, 26, pags 131-135 (ISSN 1311-7787), Mayo de 2005.
| pdf |

LIVERBIOMARK

Desarrollo de biomarcadores del grado de fibrosis hepática y del pronóstico de pacientes con enfermedades hepáticas avanzadas mediante el uso de herramientas metabolómicas, Expediente: IPT-010000-2010-013, Organismo financiador: Ministerio de Ciencia e Innovación, Programa: INNPACTO.
OWL, MD Renal, CIC bioGUNE y Ciberhed

BIODETECT

Nuevas tecnologías de detección de biomarcadores, Expediente: ER-2010/00032, Organismo financiador: Gobierno Vasco, Departamento de Industria, Comunicación y Turismo, Programa: ETORGAI.
Consorcio

OSALIVER

OSALIVER, Expediente: AB-2011/00209, Organismo financiador: Gobierno Vasco, Departamento de Industria, Comunicación y Turismo, Programa: COMPITE.
OWL

LIPIDSCORE

Diseño y desarrollo de un kit para el estudio lipidómico exhaustivo de muestras biológicas por espectrometria de masas, Expediente: IG-2012-0000346, Organismo financiador: Gobierno Vasco, Departamento de Industria, Comunicación y Turismo, Programa: GAITEK 2012.
OWL, MD Renal

PROYECTO NAFLD

PROYECTO NAFLD, Expediente: 6/12/72/2012, Organismo financiador: Diputación Foral de Bizkaia, Programa: COMPETIR (INNOVACIÓN).
OWL

2017

2017 Application of a non-invasive integrated screening approach to facilitate enrollment of clinical trials with investigational NAFLD/NASH therapeutics, Gerardo Rodríguez-Araujo, Moises Hernández, Christian Weyer, Linda Morrow, Laura Millán, Ibon Martínez-Arranz, Marcus Hompesch,
EASL, First NAFLD Summit, Rome, Italy, 09-11 November 2017.
| web | ID: P03-05 |

2017 Metabolomics approach addresses the heterogeneity of NAFLD and determines subtypes associated with different metabolic alterations, Marta Iruarrizaga-Lejarreta, Marta Varela-Rey, David Fernández-Ramos, Ibon Martínez-Arranz, Laura delaCruz-Villar, Rebeca Mayo, Arantza Peña, Juan Rodríguez-Cuesta, Liat Hayardeny, Mazen Noureddin, Cristina Alonso, Juan Anguita, María Luz Martínez-Chantar, Shelly C Lu, José M Mato,
The Liver Meeting 2017, The 68^th Annual Meeting of the American Association for the Study of Liver Diseases, Washington DC, (EEUU), October 20-24, 2017.

2017 Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis (PSC), cholangiocarcinoma (CCA) and hepatocellular carcinoma (HCC), Ander Arbelaiz, Mikel Azkargorta, Marcin Krawczyk, Alvaro Santos-Laso, Ainhoa Lapitz, Maria J. Perugorria, Oihane Erice, Esperanza Gonzalez, Raul Jimenez-Agüero, Adelaida Lacasta, Cesar Ibarra, Alberto Sanchez-Campos, Juan P. Jimeno, Frank Lammert, Piotr Milkiewicz, Marco Marzioni, Rocio I.R. Macias, Jose J. G. Marin, Tushar Patel, Gregory J. Gores, Ibon Martinez, Félix Elortza, Juan M. Falcón-Pérez, Luis Bujanda, and Jesus M. Banales,
The Liver Meeting 2017, The 68^th Annual Meeting of the American Association for the Study of Liver Diseases, Washington DC, (EEUU), October 20-24, 2017.

2017 Comprehensive NAFLD diagnosis based on a noninvasive metabolomic approach in a liquid biopsy, Puneet Puri, Ibon Martinez-Arranz, Itziar Mincholé, Michael O. Idowu, Rebeca Mayo, Jean-François Dufour, Manuel Romero-Gómez, Radan Bruha, Javier Crespo, Jesus M. Banales, Carmelo García-Monzón, Antonio Martín-Duce, Cristina Alonso, Pablo Ortiz, Mazen Noureddin, Shelly C. Lu, Pierre Bedossa, Arun J. Sanyal, José M. Mato,
The International Liver Congress^TM, Amsterdam, the Netherlands, 19-23 April.

2017 Noninvasive serum biomarkers reflect the effect of aramchol on mice fibrotic livers, Marta Iruarrizaga-Lejarreta, Laura delaCruz-Villar, Marta Varela-Rey, Rebeca Mayo, Ibon Martínez-Arranz, David Fernández-Ramos, Liat Hayardeny, Cristina Alonso, Juan Anguita, M. Luz Martínez-Chantar, José M Mato,
The International Liver Congress^TM, Amsterdam, the Netherlands, 19-23 April, 2017.

2017 Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma, Ander Arbelaiz, Mikel Azkargorta, Marcin Krawczyk, Alvaro Santos-Laso, Ainhoa Lapitz, Maria J. Perugorria, Oihane Erice, Esperanza Gonzalez, Raul Jimenez-Agüero, Adelaida Lacasta, Cesar Ibarra, Alberto Sanchez-Campos, Juan P. Jimeno, Frank Lammert, Piotr Milkiewicz, Marco Marzioni, Rocio I.R. Macias, Jose J. G. Marin, Tushar Patel, Gregory J. Gores, Ibon Martinez, Félix Elortza, Juan M. Falcón-Pérez, Luis Bujanda, and Jesus M. Banales,
The International Liver Congress^TM, Amsterdam, the Netherlands, 19-23 April, 2017.

2017 Metabolomics, Development of Metabolome-based predictors of liver diseases, Cristina Alonso, Enara Arretxe, Marta Iruarrizaga-Lejarreta, Itziar Mincholé, Rubén Gil-Redondo, Ibon Martínez-Arranz,
VALDIG Conference, Ascona (Switzerland), 19-22 February, 2017.
| poster | web |

2017 Diagnóstico y monitorización de hígado graso mediante métodos no invasivos: Correlación entre una nueva huella lipidómica en suero y cantidad de grasa hepática medida por resonancia magnética y por métodos bioquímicos, Raul Jiménez-Agüero, Enara Arretxe, Ibon Martínez-Arranz, Luis Bujanda, Jessica Arribas, Borja Lanza, Maria Jesús Pareja-Megia, Manuel Romero-Gómez, Cristina Alonso, María J Perugorria, Emma Eizaguirre, Marcin Krawczyk, Frank Lammert, Azucena Castro, Jesus M Banales,
42º congreso Anual de la AEHH, Madrid, 15-17 de Febrero de 2017.
| web |

2017 Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma, Ander Arbelaiz, Mikel Azkargorta, Marcin Krawczyk, Alvaro Santos-Laso, Ainhoa Lapitz, Maria J. Perugorria, Oihane Erice, Esperanza Gonzalez, Raul Jimenez-Agüero, Adelaida Lacasta, Cesar Ibarra, Alberto Sanchez-Campos, Juan P. Jimeno, Frank Lammert, Piotr Milkiewicz, Marco Marzioni, Rocio I.R. Macias, Jose J. G. Marin, Tushar Patel, Gregory J. Gores, Ibon Martinez, Félix Elortza, Juan M. Falcón-Pérez, Luis Bujanda, and Jesus M. Banales,
42º congreso Anual de la AEHH, Madrid, 15-17 de Febrero de 2017.
| web |

2016

2016 OWL Stat App - Una aplicación web para el análisis univariante y multivariante de datos metabolómicos, Ibon Martínez-Arranz, Itziar Mincholé, Maite Gutiérrez-Calzada, Cristina Alonso,
VIII Jornadas de Usuarios de R, Albacete, 17-18 de Noviembre, 2016.
| poster | web |

2016 Metabolomics in a liquid biopsy provides a noninvasive comprehensive NAFLD-diagnostic tool, Cristina Alonso, Puneet Puri, Ibon Martinez-Arranz, Jesús Bañales, Michael O. Idowu, Azucena Castro, Collaborative Group NASH metabolomics, Mazen Noureddin, Pierre Bedossa, José M. Mato, Arun J. Sanyal,
The 67^th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston, MA, United States on November 11-15, 2016.

2016 A non-invasive lipidomic test accurately discriminates NASH from steatosis and tracks evolution of the disease, Miriam Perez-Cormenzana, M Concepción García, Beatriz Antolin, Natalia Mora , Ibon Martinez-Arranz, De luis D. Román, Cristina Alonso, Rocío Aller,
The 67^th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston, MA, United States on November 11-15, 2016.
| web | ABSTRACT FINAL ID: 1108 |

2016 Metabolomic classification of murine and human nonalcoholic fatty liver disease, Cristina Alonso, Jose L. Lavin, Marta Iruarrizaga-Lejarreta, David Fernández, Sebastiaan van Liempd, Laura delaCruz-Villar, Nicolás Navasa, Ibon Martinez-Arranz, Igor Aurrecoechea, Xavier Buqué, Marta Varela, Juan M. Falcon-Perez, Elizabeth P. Newberry, Patricia Aspichueta, Ana M. Aransay, Mazen Noureddin, Juan Anguita, Nicholas O. Davidson, Maria L. Martinez-Chantar, Shelly C. Lu, José Mato,
The 67^th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston, MA, United States on November 11-15, 2016.
| web | ABSTRACT FINAL ID: 1603 |

2016 Translational approach to NASH diversity: learning from mouse models, Cristina Alonso, Marta Iruarrizaga-Lejarreta, Laura delaCruz-Villar, Itziar Mincholé, Ibon Martínez-Arranz, José M Mato,
Translational research in cancer cell metabolism, from 4–6 October 2016 in Bilbao, Spain
| web |

2016 A non-invasive lipidomic test accurately discriminates NASH from steatosis: A blind validation study, Javier Crespo, Ibon Martínez-Arranz, Tim Montgomery, Manuel Romero-Gómez, Rebeca Mayo, Rocío Aller de la Fuente, Joan Caballería, Daniel A. de Luis, Cristina Alonso, Libor Vitek, Radan Bruha, Pablo Ortiz,
1^st International Workshop on NASH Biomarkers, 29-30 April 2016, Washington, DC, USA
| web |

2016 Clinical validation of non-invasive lipidomic test for the diagnosis of Non-Alcoholic Fatty Liver Disease (NAFLD), Patricia Salvador, Sonia Blanco, Nahikari Maria Irazabal-Remuiñan, Ibon Martínez-Arranz, Luis Francisco Eraña-Ledesma, Itziar Mincholé, Fernando Menéndez, Rebeca Mayo, Pablo Ruiz, Raquel González-Monasterio, Elvira Delgado, Juan Ignacio Arenas, Maider Martos, Antxon Otegui, Gixane Arregui, María Carmen Eizmendi, Sagrario Urquiola, Ricardo San Vicente, Azucena Castro, Pablo Ortiz, Jose Ignacio Pijoán, Javier Bustamante,
EASL, European Association for the Study of the Liver 2016, Barcelona, April 13-17, 2016.
| poster |

2016 A non-invasive lipidomic test accurately discriminates NASH from steatosis: A blind validation study, Javier Crespo, Ibon Martínez-Arranz, Manuel Romero-Gómez, Rebeca Mayo, Rocío Aller de la Fuente, Joan Caballería, Cristina Alonso, Libor Vitek, Pablo Ortiz, Radan Bruha,
EASL, European Association for the Study of the Liver 2016, Barcelona, April 13-17, 2016.

2016 Validación del test OWLiver de segunda generación, un test lipidómico no invasivo para el seguimiento de la enfermedad de higado graso, María Teresa Arias-Loste, Paula Iruzubieta, Antonio Cuadrado, Emilio Fábrega, Ibon Martínez-Arranz, Azucena Castro, Will García, Javier Crespo,
41º Congreso Anual de la AEHH, Madrid, 17-19 de Febrero de 2016.

2016 Evaluación prospectiva en ciego del test lipidómico OWLiver como diagnóstico de enfermedad hepática grasa no alcohólica, R., Aller, C. Alonso, Ibon Martínez-Arranz, MC., García, E., Berroa, C. Tafur, N., Mora, G. González, S. Lorenzo, DA., de Luis,
41º Congreso Anual de la AEHH, Madrid, 17-19 de Febrero de 2016.

2016 A novel non-invasive lipidomic test for the diagnosis and follow-up of NAFLD patients, R. González-Monasterio, P. Salvador, Ibon Martínez-Arranz, N.M. Irazabal-Remuiñan, L.F. Eraña-Ledesma, I. Mincholé, S. Blanco, P. Ruiz, F. Menéndez, R. Mayo, Will García, E. Delgado, J.I. Arenas, M. Martos, A. Otegui, G. Arregi, M.C., Eizmendi, S. Urquiola, R. San Vicente, A. Castro, P. Ortiz, J.I. Pijoán, J. Bustamante,
XXV Congrés de la Societat Catalana de Digestologia, Reus, 30 de Enero, 2016.

2015

2015 Subtyping nonalcoholic steatohepatitis for the development of effective treatments, Ibon Martínez-Arranz, Cristina Alonso, David Fernández, Rebeca Mayo, Marta Varela, Mazen Noureddin, Maria L. Martinez-Chantar, Shelly C. Lu, Azucena Castro, Jose M. Mato,
The Liver Meeting 2015, The 66^th Annual Meeting of the American Association for the Study of Liver Diseases, San Francisco, CA (EEUU), November 13-17, 2015., Hepatology, Volume 62, Number 1 (Suppl) – October 2015, Pages 93A–207A.
| doi |

2015 S-Adenosylmethionine Treatment Corrects Deregulated Lipid Metabolic Pathways and Prevents Progression of Non-Alcoholic Steatohepatitis in Methionine Adenosyltransferase 1a Knockout Mice, David Fernández, Cristina Alonso, Sebastiaan van Liempd, Marta Varela, Nicolás Navasa, Ibon Martínez-Arranz, Patricia Aspichueta, Ana M. Aransay, Juan Anguita, Juan M. Falcón-Perez, M aria L. Martinez-Chantar, Shelly C. Lu, Jose M. Mato,
The Liver Meeting 2015, The 66^th Annual Meeting of the American Association for the Study of Liver Diseases, San Francisco, CA (EEUU), November 13-17, 2015., Hepatology, Volume 62, Number 1 (Suppl) – October 2015, Pages 93A–207A.
| doi |

2015 The lipidomic signature of disease progression in nonalcoholic fatty liver disease (NAFLD), Cristina Alonso, Amon Asgharpour, Ibon Martínez-Arranz, Puneet Puri, Mohammad S. Siddiqui, Pablo Ortiz, Jose M. Mato, Arun J. Sanyal,
The Liver Meeting 2015, The 66^th Annual Meeting of the American Association for the Study of Liver Diseases, San Francisco, CA (EEUU), November 13-17, 2015.,
Hepatology, Volume 62, Number 1 (Suppl) – October 2015, Page 1262A.
| poster |

2015 The metabolic structure of nonalcoholic steatohepatitis, Cristina Alonso, David Fernandez-Ramos, Ibon Martínez-Arranz, David Balgoma, Sebastiaan M van Liempd, Mazen Noureddin, Patricia Aspichueta, M Luz Martínez-Chantar, Shelly C Lu, José M Mato,
Metabolomics 2015, Burlingame, San Franscisco Bay, CA (EEUU), June 29-July 2, 2015.
| web |

2015 OWL Stat App - An interactive web-application for univariate and multivariate metabolomics data analysis, Ibon Martínez-Arranz, Maite Gutiérrez-Calzada, David Balgoma, Cristina Alonso,
Metabolomics 2015, Burlingame, San Franscisco Bay, CA, June 29-July 2, 2015.
| poster | web |

2015 OWL Stat App - An interactive web-application for univariate and multivariate metabolomics data analysis, Ibon Martínez-Arranz, Maite Gutiérrez-Calzada, David Balgoma, Cristina Alonso,
Science+, Encuentro para estudiantes y profesionales de la Ciencia, Bilbao, 7-9 de Mayo de 2015.

2015 Lipidomic signature linked to alcoholic hepatitis: characterization of ether-linked glycerophospholipids, Cristina Alonso, Javier Michelena, Ainara Cano, Jose Altamirano, Ibon Martínez-Arranz, David Balgoma, Ramón Bataller, Jose M. Mato, Juan Caballería,
Science+, Encuentro para estudiantes y profesionales de la Ciencia, Bilbao, 7-9 de Mayo de 2015.

2015 Identification of serum metabolites associated with cholestatic pruritus, Albert Parés, David Balgoma, Anna Reig, Ibon Martínez-Arranz, Azucena Castro, Antoni Mas,
EASL, European Association for the Study of the Liver 2015, Vienna, Abril de 2015.
Journal of Hepatology, Volume 62, S787–S788.

2015 A metabolic definition of NASH and its resolution by S-Adenosylmethionine in Mat1a KO mice, José M Mato, David Fernandez-Ramos, Ibon Martínez-Arranz, Rebeca Mayo, Sebastiaan M van Liempd, Holger Sann, Julian Platon, Mazen Noureddin, Patricia Aspichueta, Cristina Alonso, M Luz Martínez-Chantar, Shelly C Lu, EASL, European Association for the Study of the Liver 2015, Vienna, Abril de 2015.
Journal of Hepatology, Volume 62, Page S717.
| doi |

2015 A metabolic definition of NASH and its resolution by S-Adenosylmethionine in Mat1a KO mice, David Fernandez-Ramos, Ibon Martínez-Arranz, Rebeca Mayo, Sebastiaan M van Liempd, Holger Sann, Julian Platon, Mazen Noureddin, Patricia Aspichueta, Cristina Alonso, M Luz Martínez-Chantar, Shelly C Lu, José M Mato,
Liver Metabolism and Nonalcoholic Fatty Liver Disease, Whistler, British Columbia, Canada, Marzo de 2015.

2015 Incidence of non-alcoholic fatty liver disease in non-obese and non-diabetic individuals during normal aging, Pablo Ortiz, Rebeca mayo, Miriam Pérez-Cormenzana, Ibon Martínez-Arranz, M.L. Martínez-Chantar, S.C. Lu, J.M. Mato,
Industry Colloquium: Novel Targets and Therapies in Liver Disease, Durham, North Carolina, March 20-21, 2015.
| poster |

2014

2014 Lipidomic signature linked to alcoholic hepatitis: characterization of ether-linked glycerophospholipids, Cristina Alonso, Javier Michelena, Ainara Cano, Jose Altamirano, Ibon Martínez-Arranz, David Balgoma, Ramón Bataller, Jose M. Mato, Juan Caballería, Metabomeeting 2014, London, Septiembre de 2014.
| poster |

2014 Deciphering non alcoholic fatty-liver disease lipidomic fluxes, Ainara Cano, Cristina Alonso, Miriam Pérez-Cormenzana, Rebeca Mayo, Ibon Martínez-Arranz, Azucena Castro, Biochemical Society, Advancing Molecular Bioscience, Abruzzo (Italy), Mayo de 2014.
| abstract | web | Reference ID: P010 |

2014 The adipogenic lipidome of obese rat offspring is reversed by slow digesting carbohydrate diets during pregnancy. NIGOhealth study, López-Pedrosa J.-M., Manzano M., Martin M.-J., Bueno P., Cano A., Castro A., Mayo R., Martinez I., Rueda R.,
International Conference on Developmental Origins of Adiposity and Long-term Health, Munich (Alemania), Marzo de 2014.
| web |

2013

2013 The signature biomarkers serum lipids of alcoholic steatohepatitis, Cristina Alonso, Javier Michelena, Ibon Martinez-Arranz, Jose Altamirano, Rebeca Mayo, Ramón Bataller, Jose M. Mato, Juan Caballería,
The Liver Meeting 2013, The 64^nd Annual Meeting of the American Association for the Study of Liver Diseases, Washington (EEUU), Noviembre de 2013.

2013 El exceso de S-adenosilmetionina deriva la fosfatidiletanolamina hacia la síntesis de fosfatidilcolina y de triglicéridos, Maite Martínez Uña, Marta Varela-Rey, Ainara Cano, Larraitz Fernández-Ares, Naiara Beraza, Igor Aurrekoetxea, Ibon Martínez-Arranz, Juan L García-Rodríguez, Xabier Buqué, Daniela Mestre, Zigmund Luka, Conrad Wagner, Cristina Alonso, Richard H Finnell, Shelly C Lu, M Luz Martínez-Chantar, Jose M Mato, Patricia Aspichueta,
XXXVI Congreso de la Sociedad Española de Bioquímica y Biología Molecular, Madrid, Septiembre de 2013.

2013 Signature lipid biomarker analisis of non-alcoholic liver disease, Cristina Alonso, Ibon Martínez-Arranz, Rebeca Mayo, Miriam Pérez-Cormenzana, Ainara Cano, Joan Caballería, Azucena Castro,
9^th Annual Conference of the Metabolomics Society, Glasgow (Scotland), Julio de 2013.
| poster |

2012

2012 Metabolic profile associated with alcoholic hepatitis and the response to treatment. Preliminary results, Javier Michelena, Cristina Alonso, José Altamirano, Ibon Martínez-Arranz, Ramón Bataller, MariaLuz Martínez-Chantar, Azucena Castro, Jose M. Mato, Juan Caballería,
The Liver Meeting 2012, The 63^nd Annual Meeting of the American Association for the Study of Liver Diseases, Boston, Massachusetts (EEUU), Noviembre de 2012.
| Reference ID: 1363 |

2012 Lipidomic Profiling of Dried Serum Spots (DSS), Mayo, R., Martínez-Arranz, I., Ispizua, Z., Alonso, C., Tandrón, Y., Pérez-Cormenzana, M.,
2^nd Metabolomics & Proteomics Workshop 2012, CIC bioGune, Bilbao, Spain, October, 1-3^rd 2012, Bilbao (España), Octubre 2012.
| poster |

2012 Software Tools for UPLC-MS Metabolomics, Mincholé, I., Martínez-Arranz, I., Falcón, JM., Tandrón, Y.,
2^nd Metabolomics & Proteomics Workshop 2012, CIC bioGune, Bilbao, Spain, October, 1-3^rd 2012, Bilbao (España), Octubre 2012.
| poster |

2012 Lipidomic Profiling of Dried Serum Spots (DSS), Mayo, R., Martínez-Arranz, I., Ispizua, Z., Alonso, C., Tandrón, Y., Pérez-Cormenzana, M.,
Metabomeeting 2012, Manchester (UK), Septiembre 2012.
| poster |

2012 Utilidad de la metabolómica para establecer la gravedad y predecir la respuesta al tratamiento en la hepatitis alcohólica. Resultados preliminares, Michelena, J., Alonso, C., Barr, J., Altamirano, J., Martínez-Arranz, I., Bataller, R., Martínez Chantar, M.L., Castro, A., Mato, J.M., Caballería, J.,
XXXVII Congreso Anual de la Asociación Española para el Estudio del Hígado (AEEH), Madrid (España), Febrero 2012.

2012 Perfiles metabólicos dependientes de la obesidad asociados a la progresión del hígado graso no alcohólico, Barr, J., Caballería, J., Martínez-Arranz, I., Domínguez-Díez, A., Muntané, J., Pérez-Cormenzana, M., García-Monzón, C., Mayo, R., Martín-Duce, A., Romero-Gómez, M., Lo Iacono, O., Clément, K., Andrade, R., Pérez-Carreras, M., Gual, P., Fernández-Escalante, C., Arévalo, E., García-Unzueta, M.T., Tordjman, J., Crespo, J., le Marchand Brustel, Y., Gómez Fleitas, M., Martínez Chantar, M.L., Castro, A., S.C. Lu, Alonso, C., Vázquez Chantada, M., Mato, J.M.,
XXXVII Congreso Anual de la Asociación Española para el Estudio del Hígado (AEEH), Madrid (España), Febrero 2012.

2011

2011 The development of metabolome-based predictors of nonalcoholic fatty liver disease, Barr, J., Caballería, J., Martínez Arranz, I., Domínguez Díez, A., Alonso, C., Muntané, J., Pérez Cormenzana, M., García Monzón, C., Mayo, R., Martín Duce, A., Romero Gómez, M., Lo Iacono, O., Tordjman, J., Andrade, R.J., Pérez Carreras, M., le Marchand Brustel, Y., Tran, A., Fernández Escalante, C., Arévalo, E., García Unzueta, M., Clement, K., Crespo, J., Gual, P.,Gómez Fleitas, M., Martínez Chantar, M.L., Castro, A., S.C. Lu, Vázquez Chantada, M., Mato, J.M.,
7^th Annual Advances in Metabolic Profiling conference and exhibition, Dublin (Ireland), Noviembre de 2011.
| poster | Poster Award Winner |

2011 Metabolic profiling as noninvasive tool for nonalcoholic steatohepatitis diagnosis, Barr, J., Caballería, J., Martínez Arranz, I., Domínguez Díez, A., Alonso, C., Muntané, J., Pérez Cormenzana, M., García Monzón, C., Mayo, R., Martín Duce, A., Romero Gómez, M., Lo Iacono, O., Tordjman, J., Andrade, R.J., Pérez Carreras, M., le Marchand Brustel, Y., Tran, A., Fernández Escalante, C., Arévalo, E., García Unzueta, M., Clement, K., Crespo, J., Gual, P.,Gómez Fleitas, M., Martínez Chantar, M.L., Castro, A., S.C. Lu, Vázquez Chantada, M., Mato, J.M.,
The Liver Meeting 2011, The 62^nd Annual Meeting of the American Association for the Study of Liver Diseases, San Francisco (EEUU), Noviembre de 2011.
| poster |

2011 Utilización de donantes añosos en el trasplante renal, García-Olaverri Rodríguez, J., Elorrieta, P., Esnaola, K., Rodríguez, P., Marrón, I., Uriarte, I., Martínez-Arranz, I., Aranzabal, J., Moratalla Basante, A., Zabala Egurrola, J.A., Pertusa Peña, C.,
XXV Reunión del Grupo de Trasplante, Córdoba (España), Marzo de 2011.

2011 Trasplante Renal con Donantes añosos (>65 años): Experiencia de 6 años, Elorrieta, P., Esnaola, K., Gainza, F.J., Zabala, A., Rodríguez, P., Marrón, I., Uriarte, I., Martínez-Arranz, I., Pertusa, C., Aranzabal, J.,
XXV Reunión del Grupo de Trasplante, Córdoba (España), Marzo de 2011.

2010

2010 Utilidad de la Unidad de Información de pacientes renales del País Vasco (UNIPAR), Magaz Lago, A., Aranzabal Pérez, J., Martínez-Arranz, I., Saracho Rotaeche, R., Aguirre, R., Ariceta Iraola, G., Argoitia Urresti, A., Maza, A., Minguela Pesquera, I., Rodrigo de Tomás, M.T.,
XL Congreso Nacional de la Sociedad Española de Nefrología, Granada (España), Octubre de 2010.
| web | web |

2009

2009 Impacto del fracaso del injerto y el retrasplante en la supervivencia de diálisis, Saracho Rotaeche, R., Moina Eguren, I., Montenegro Martínez, J., Inza, A., Iribar, I., Maza, A., Celayeta, A., Olivar, E., Gimeno, I., Magaz lago, A., Martínez-Arranz, I.,
XXXIX Congreso Nacional de la Sociedad Española de Nefrología, Pamplona (España), Octubre de 2009.
| web | web |

2009 Supervivencia de pacientes en diálisis tras la pérdida del primer injerto. Comparativa con pacientes que inician diálisis sin trasplante previo. Experiencia en el País Vasco, Rodrigo de Tomás, M.T., Porto, M., Lampreabe Gaztelu, I., García Erauzkin, G., Saracho Rotaeche, R., Magaz Lago, A., Martínez-Arranz, I., Aguirre, R., Argoitia Urresti, A., Ariceta Iraola, G., Ruiz de Gauna, R., Maza, A., Moina Eguren, I., Viana Apraiz, F.,
XXXIX Congreso Nacional de la Sociedad Española de Nefrología, Pamplona (España), Octubre de 2009.
| web | web |

2009 New test set to assess Logical Intelligence: CERVANTES, Magaz Lago, A., García Pérez, E.M., Martínez-Arranz, I., Sarrionandia-Ibarra, L.,
10^th European Conference on Psychological Assessment, Ghent (Bélgica), Septiembre de 2009.

2008

2008 Trasplante Renal con Donantes Mayores de 65 años, F.J. Gainza, J. Aranzabal, S. Zárraga, G. García Erauzki, I. Martínez-Arranz, A. Magaz,
XXXVIII Congreso de la Sociedad Española de Nefrología, San Sebastián, Octubre de 2008.
| web |

2008 Explanation model of the evolution of the End-Stage Renal Disease (ESRD) in the Basque Country, 1991-2002, Saracho Rotaeche, R., Rodrigo de Tomás, M.T., Argoitia Urresti, A., Moina Eguren, I., Viana Apraiz, F., García Erauzkin, G., Aguirre, R., Maza, A., Martínez-Arranz, I., Magaz Lago, A.,
XLV ERA-EDTA Congress, Estocolmo (Suecia), Mayo de 2008.

2007

2007 Do the differences in prevalence of hipertension and diabetes justify the regional differences of ESRD?, Moina Eguren, I., Arrieta Lezama, J., Rodrigo de Tomás, M.T., Saracho Rotaeche, R., García Erauzkin, G., Argoitia Urresti, A., Maza, A., Gimeno, I., Viana Apraiz, F., Aguirre, R., Martínez Arranz, I., Magaz Lago, A.,
XLIV ERA-EDTA Congress, Barcelona (España), Junio de 2007.

2006

2006 Prevalencia de la IRC en la edad pediátrica en Euskadi. Informe preliminar, Ariceta Iraola, G., Aguirre, M., Areses, R., Orive, B., Sánchez, M.C., Martínez-Arranz, I., Magaz Lago, A.,
XXXII Congreso Nacional de Nefrología Pediátrica, Oviedo (España), Noviembre de 2006.

2004

2004 Influencia de las características del donante en la funcionalidad del injerto renal a medio y largo plazo, Pérez Beltrán, M.R., Moina Eguren, I., Martínez-Arranz, I., Corral Carames, F., Zárraga Larrondo, S., Magaz Lago, A., Aranzabal Pérez, J., Arrieta Lezama, J.,
XIX Reunión Nacional e Iberoamericana de Coordinadores de Trasplantes, Tenerife (España), Mayo de 2004.

2004 Depresión y supervivencia en enfermos renales crónicos, Magaz Lago, A., Bragado, C., Arrieta Lezama, J., Aranzabal Pérez, J., Martínez-Arranz, I.,
XIII Congreso de Nefrología e Hipertensión de Latinoamérica, Punta del este (Uruguay), Abril de 2004.

blog

I write a data science blog at imarranz.com where I apply Mathematics and R to open datasets and write-up the results. My original wordpress blog (www.fdesnedecor.wordpress.com) has my experience in Data Science.